Difference between marevan and coumadin warfarin

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Warfarin is the most frequently prescribed antithrombotic agent, available in Australia as brands Coumadin and Marevan.

Is switching anticoagulant brands safe – Coumadin and Marevan? | Australian Medical Student Journal

Although both are manufactured by Aspen Pharmaceuticals, there are differences in formulation. The product information states they cannot be used interchangeably. Two incident reports of warfarin brand interchange in our hospital prompted a literature review.

We aimed to review published evidence on the pharmacokinetics and bioequivalence of different warfarin brands and make brand switching recommendations. Warfarin review of and coumadin literature on warfarin warfarin and incidents difference between marevan by the Therapeutic Goods Administration Difference between. Difference between marevan studies explored different warfarin formulations.

No significant differences were found in efficacy with brand switching in eight studies analysing participants who were healthy, had atrial fibrillation AFor a mechanical warfarin valve. Prospective observational studies demonstrated no significant difference in the International Normalised Ratio INR or adverse events, however, a retrospective observational study demonstrated warfarin link in complications.

Of the four population studies, only one demonstrated elevated rates difference between marevan and coumadin warfarin haemorrhage or thrombosis. No studies directly compared Coumadin and Marevan.

Marevan Tablets -

Three Warfarin case reports describe adverse events from brand switching. Studies of different warfarin formulations demonstrate bioequivalence in population studies, but with marked inter-individual variation, hence the recommendation is to continue the same brand of warfarin where possible.

If substituting or brand switching, close monitoring with frequent INR testing is suggested. Warfarin is the most frequently prescribed antithrombotic agent in Australia.

Is switching anticoagulant brands safe – Coumadin and Marevan?

Indications include both prevention and treatment of thrombosis, prevention of strokes associated with atrial fibrillation AF as well as clotting difference between marevan and coumadin warfarin mechanical heart valves. The article source of warfarin need to be weighed against the risk of haemorrhage, a common complication seen in patients prescribed these anticoagulants.

In Australia, difference between marevan and coumadin warfarin are two brands of warfarin: Prescribing bodies within Australia, including the Therapeutic Goods Administration TGA and the National Prescribing Service do not recommend interchanging warfarin brands, Coumadin and Marevandue to the lack of information on bioequivalence.

Two locally reported incidents involving brand switching marevan and coumadin to a review of the literature to inform practice.

One of the incidents involved a year-old and coumadin patient who mistakenly received Coumadin, when Marevan was difference between marevan and coumadin warfarin usual brand. The nurse administering the nocte medications quickly discovered this incident. The second patient was an year-old female admitted to hospital after a fall and did not receive her regular prescribed Marevan dose, as staff were unable to source that brand after-hours.

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