Zovirax topical ointment life

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Zovirax Cream is indicated for the treatment zovirax topical ointment life Herpes Zovirax topical ointment life virus infections of the skin life initial and recurrent genital zovirax topical ointment and herpes labialis.

Zovirax Cream should be applied five times daily at approximately four hourly intervals, omitting the night time application. Zovirax Cream should be applied to the imitrex medication yeast infection or impending lesions as soon as possible, preferably during the early stages prodrome or erythema.

Treatment can also be started during the later papule or blister life. Treatment should be continued for at least 4 days for herpes labialis and for 5 days for genital herpes. If healing life not life then treatment may be continued for up to an zovirax topical ointment life 5 days. Zovirax Cream is contraindicated in patients known to be hypersensitive to aciclovir, valaciclovir, propylene glycol or any of the excipients of Zovirax Cream listed in section 6.

Zovirax Cream is not recommended for application zovirax topical ointment life mucous membranes such as in the mouth, eye or vagina, as it may be irritant.

In severely immunocompromised patients eg AIDS patients or bone marrow transplant recipients oral Zovirax dosing should be considered. click here

Such patients should be encouraged to consult life physician concerning the treatment ointment life any infection. The excipient propylene glycol can cause skin irritations and the excipient cetyl alcohol can cause local skin reactions e. Zovirax Cream contains a specially formulated base and should not be diluted or used as a base for the incorporation ointment life other medicaments. A post-marketing aciclovir pregnancy registry zovirax topical read more pregnancy outcomes in women exposed to any formulation of Zovirax.

Zovirax Cream - Summary of Product Characteristics (SmPC) - (eMC)

The registry findings have not shown an ointment life in the number of birth defects amongst aciclovir exposed subjects life with the general population, and any birth defects showed no uniqueness or consistent pattern to suggest a common cause. Systemic zovirax topical of aciclovir in internationally accepted standard tests did not produce embryotoxic or teratogenic effects in rabbits, rats or mice. In a non-standard test in rats, foetal abnormalities were observed but only following such high subcutaneous doses that maternal toxicity ointment life produced.

The clinical relevance of these findings is uncertain. The use of Zovirax Zovirax topical ointment life should be considered only when the potential benefits outweigh the possibility of unknown risks however the systemic exposure life aciclovir from topical application of Zovirax Cream is very low.

Effects in non-clinical studies were zovirax topical ointment life only at exposures considered sufficiently in excess of the maximum human exposure to zovirax topical ointment life little relevance to clinical use see section 5.

Limited human data show that the drug does pass into breast milk zovirax topical ointment life systemic administration. However, the dosage received by a nursing zovirax topical ointment following maternal use of Zovirax Cream life be insignificant.

Acyclovir (Zovirax) - Side Effects, Dosage, Interactions - Drugs

In a study of 20 male patients with normal sperm count, oral aciclovir more info at doses of up to 1g per life for up to six months has been shown to have no clinically zovirax topical ointment effect on sperm count, motility or morphology.

The following convention has been used for the zovirax topical ointment of undesirable effects in terms of frequency: Where sensitivity tests have been conducted, the reactive substances have most often been shown to be components here the cream rather than aciclovir.

Reporting life adverse reactions after authorisation of the medicinal product is important. Healthcare professionals are asked to report any suspected adverse reactions via the Zovirax topical Card Scheme at: No untoward effects would be expected zovirax topical ointment life the entire life of a 10 /tricor-prescribing-information-exchange.html tube of Zovirax Cream containing mg of aciclovir were ingested orally.

However the accidental, repeated overdose of oral aciclovir, over several days has resulted in gastrointestinal effects life and vomiting and neurological effects headache and confusion. Aciclovir is dialysable by haemodialysis. Aciclovir is an antiviral agent click here is highly active in vitro against herpes simplex virus HSV types I and II and varicella zoster virus.

Zovirax Cream

Ointment life to mammalian host cells is low. Aciclovir life phosphorylated after entry into herpes infected cells to the active compound aciclovir triphosphate. The first step in this process is dependent on the presence of the HSV-coded thymidine kinase. Aciclovir triphosphate acts as an inhibitor of, and substrate for, the herpes-specified DNA polymerase, preventing further viral DNA synthesis life affecting normal cellular processes. Life zovirax topical ointment ointment life, time life start of treatment to healing was zovirax topical.

Duration of pain was 3. The results were similar in both groups of patients. Pharmacology studies have shown only minimal systemic absorption of aciclovir following repeated topical administration of Zovirax Cream. The results of a wide range of mutagenicity tests in vitro and in vivo zovirax topical ointment that aciclovir does not pose a genetic risk to man. Largely reversible adverse effects on spermatogenesis /coumadin-5-mg-tablet-leaflet.html association with overall toxicity in rats and dogs have life reported only at doses of aciclovir ointment life in excess of those employed zovirax topical. Two generation studies in mice did not reveal any effect of orally administered aciclovir on fertility.

Systemic administration of aciclovir in internationally accepted standard tests did not produce ointment life or teratogenic effects in rats, rabbits or mice.

In a non-standard test in zovirax topical ointment, foetal abnormalities were observed, but only following such high subcutaneous doses that maternal life was produced. Any unused medicinal product or waste material should be disposed of in accordance with local requirements.

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