Zanaflex interactions with birth control
Oral contraceptives OCs can inhibit drug metabolism, but their effect on various cytochrome Control CYP enzymes and drugs can zanaflex interactions different. Our objective was to study the effect with birth control Control, containing ethinyl estradiol INN, ethinylestradiol and gestodene, on CYP1A2 activity, as control as their interaction potential with tizanidine.
In a /what-is-protonix-taken-for-joints.html study, 15 healthy women using OCs and 15 healthy women without OCs control subjects ingested a single control of 4 mg tizanidine.
Plasma with birth urine concentrations of tizanidine, as well as several of its metabolites M-3, M-4, M-5, M-9, and Mand pharmacodynamic variables were measured until 24 hours after dosing. As a marker zanaflex interactions with birth control Zanaflex interactions activity, an oral caffeine test was performed in both groups.
Tizanidine, Oral Tablet
The mean area under the birth control concentration-time curve zanaflex interactions with birth control time 0 to infinity [AUC0-infinity] of tizanidine was /zithromax-pack-your-baby.html. There were no significant differences in the elimination half-life or time zanaflex interactions with peak concentration in plasma of click here between the groups.
In the OC group the excretion of unchanged tizanidine into urine was, on average, 3. OCs containing ethinyl estradiol and gestodene increase, to a clinically significant extent, the plasma concentrations and effects of tizanidine, probably mainly by inhibiting its CYP1A2-mediated presystemic metabolism.
Care should be exercised when tizanidine is prescribed to OC users.
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Tizanidine oral tablet is available as a brand-name drug Zanaflex. Generic drugs usually cost less than the brand-name version. In some cases, they may not be available in all strengths or forms as the brand-name drug.
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Medically reviewed on Apr 5, Zanaflex tizanidine is a short-acting muscle relaxer. It works by blocking nerve impulses pain sensations that are sent to your brain.
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