Robaxin 500 mg oral tablet 70 mg
Medically reviewed on Sep 1, The chemical name of methocarbamol is 3- 2-methoxyphenoxy -1,2-propanediol 1-carbamate and has the empirical formula C 11 H 15 NO 5.
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Its molecular weight is The structural formula is shown below. Methocarbamol is a white powder, sparingly soluble in water and chloroform, soluble in alcohol only with heating and propylene glycol, and insoluble in benzene and n -hexane.
It has no direct action on the robaxin 500 mechanism of striated muscle, the motor end plate or the nerve fiber. In healthy volunteers, the plasma robaxin 500 mg oral tablet 70 mg of methocarbamol ranges between 0.
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Methocarbamol is metabolized via dealkylation and hydroxylation. Conjugation of methocarbamol also is likely.
Essentially all methocarbamol metabolites are eliminated in the urine. Small amounts of unchanged methocarbamol also are excreted in the urine. The mode of action of methocarbamol has not been clearly identified, but may be related to its sedative properties.
Methocarbamol does not directly relax tense skeletal muscles in man. There have been reports of fetal and congenital abnormalities following in utero exposure to methocarbamol. Patients should be cautioned about operating machinery, including automobiles, until they are reasonably certain that methocarbamol therapy does not adversely affect their ability to engage in such activities.
Patients should be cautioned that methocarbamol may cause drowsiness or dizziness, which robaxin 500 mg oral tablet 70 mg impair their ability to operate motor vehicles or machinery.
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Because methocarbamol may possess a general CNS-depressant effect, patients should be cautioned about check this out effects with alcohol and other CNS depressants. Methocarbamol may inhibit the effect of pyridostigmine bromide. Therefore, methocarbamol should be used with caution in patients with myasthenia gravis receiving anticholinesterase agents.
Methocarbamol may cause a color interference /medication-voltaren-gel-long-term-use.html certain screening tests tablet 5-hydroxyindoleacetic acid 5-HIAA using nitrosonaphthol reagent and in screening tests for urinary vanillylmandelic acid VMA using the Gitlow method. Long-term studies to evaluate the carcinogenic potential of methocarbamol have not been performed.
No studies have been oral tablet 500 oral tablet oral tablet 70 mg to assess the effect of methocarbamol on mutagenesis or its potential robaxin 500 impair fertility.
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Animal reproduction studies robaxin 500 mg oral tablet 70 mg not been conducted with methocarbamol. It is also not known whether methocarbamol can cause fetal harm when administered to a pregnant woman robaxin 500 mg oral tablet 70 mg can affect reproduction capacity.
Adverse reactions reported coincident with the administration of methocarbamol include:. Body as a whole: Anaphylactic reaction, angioneurotic edema, fever, headache.
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Bradycardia, flushing, hypotension, syncope, thrombophlebitis. Dyspepsia, jaundice including oral tablet jaundicenausea and vomiting. Amnesia, confusion, diplopia, dizziness or lightheadedness, drowsiness, insomnia, mild this web page incoordination, nystagmus, sedation, seizures including grand malvertigo.
Oral tablet and /rosuvastatin-diabetes-life-expectancy.html senses: Blurred vision, conjunctivitis, nasal congestion, robaxin 500 mg oral tablet 70 mg taste, pruritus, rash, urticaria. Limited information is available on the acute toxicity of methocarbamol. Robaxin 500 of methocarbamol is frequently in conjunction with alcohol or other CNS depressants and includes the following symptoms: In post-marketing experience, deaths have been reported with an overdose of methocarbamol alone or in the presence of other CNS depressants, alcohol or psychotropic drugs.
Management of overdose includes symptomatic and supportive treatment. Supportive measures include maintenance of an adequate airway, monitoring urinary output and robaxin 500 mg oral tablet 70 mg signs, and administration of intravenous fluids if necessary.
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The usefulness of hemodialysis in managing overdose is unknown. Six grams a day are recommended for the first 48 to 72 hours of treatment. For severe conditions 8 grams a day may be administered. Thereafter, oral tablet dosage can usually be reduced to approximately 4 grams here day.
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As a short-term adjunct to the symptomatic treatment of acute musculoskeletal disorders associated with painful muscle spasms. The usual dose is 2 tablets four times daily but therapeutic response has been achieved with doses as low as 1 tablet three times daily. In patients with chronic hepatic disease the elimination half-life may be prolonged.
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