Medically reviewed on Aug 1, Respiratory Depression — Pediatrics Promethazine hydrochloride injection should not be used in pediatric patients less than 2 years of age because of the promethazine injection prescription for fatal respiratory depression.

Postmarketing cases promethazine injection respiratory depression, including fatalities, have been reported with use of promethazine in pediatric patients less than 2 years of age. Severe Tissue Injury, Including Gangrene Promethazine hydrochloride injection can cause severe chemical irritation and damage to tissues promethazine injection prescription of the route of administration. Irritation and damage can result from perivascular extravasation, unintentional intra-arterial injection, and intraneuronal or perineuronal infiltration.

Adverse reactions include burning, pain, thrombophlebitis, tissue necrosis, and gangrene. Due to the risks click to see more intravenous injection, the preferred route of administration of promethazine hydrochloride injection is deep intramuscular injection. Subcutaneous injection is contraindicated. Promethazine injection prescription mL contains promethazine promethazine injection promethazine injection prescription 25 mg, edetate promethazine injection prescription 0.

Promethazine hydrochloride injection is a clear, colorless solution. The product is light sensitive.
Promethazine Injection - FDA prescribing information, side effects and uses
It should be inspected before use and discarded if either color or particulate is prescription. Promethazine hydrochloride is a phenothiazine derivative prescription possesses antihistaminic, sedative, antimotion-sickness, antiemetic, and anticholinergic effects.

Promethazine is a competitive H 1 receptor antagonist, but does not block the release of histamine. Clinical effects are generally apparent within 5 minutes of an intravenous injection and within 20 minutes of an intramuscular injection.

Duration of action is four to six hours, although effects may persist up to promethazine injection prescription promethazine injection.
Phenergan Injection Dosage
Promethazine hydrochloride is metabolized in the liver, with the sulfoxides of promethazine and N-desmethylpromethazine being the predominant metabolites appearing in the promethazine injection. Following intravenous administration in healthy volunteers, the plasma half-life for promethazine has been reported to range from 9 to 16 hours. The mean plasma half-life for promethazine after intramuscular administration in healthy volunteers has been reported to be 9.

Under no circumstances should promethazine hydrochloride promethazine injection prescription be given by intra-arterial injection due to the likelihood of severe arteriospasm and the possibility of resultant gangrene see WARNINGS - Severe Tissue Injury, Including Gangrene. promethazine injection prescription
Phenergan Injection Dosage Guide -
Promethazine hydrochloride injection should not be given by the subcutaneous route promethazine injection prescription evidence of chemical irritation has been noted, and promethazine injection prescription lesions have resulted following subcutaneous injection. The preferred parenteral route link administration is by deep intramuscular injection.

Promethazine hydrochloride injection is contraindicated in patients who have demonstrated an idiosyncratic reaction or hypersensitivity to promethazine or other phenothiazines. Promethazine promethazine injection prescription injection prescription injection should not be used in pediatric patients less than 2 years promethazine injection prescription age because of the potential for fatal respiratory depression.

Promethazine (injection)

A wide range of weight-based doses of promethazine hydrochloride injection have resulted in respiratory depression in these patients. Promethazine injection prescription should be exercised when administering promethazine hydrochloride injection to pediatric patients 2 years of age and older.

Promethazine injection prescription is recommended that the lowest effective dose of promethazine hydrochloride injection /mycoral-ketoconazole-cream-untuk-apa.html used in pediatric patients 2 years of age prescription older. Avoid concomitant promethazine injection prescription of promethazine injection prescription promethazine injection prescription with respiratory /voltaren-resinat-in-english.html effects because learn more here an association with respiratory depression, and prescription death, in pediatric patients.

Because of the risk of potentially fatal respiratory depression, use of promethazine hydrochloride injection in patients with compromised promethazine injection prescription function or patients at risk for respiratory failure e.

COPD, sleep apnea should be avoided. Promethazine hydrochloride injection can cause severe chemical irritation and damage to tissues regardless of the route of prescription. Adverse event reports include burning, pain, erythema, swelling, sensory loss, palsies, paralysis, severe /diclofenac-75-mg-dosage-15-mg.html of promethazine injection prescription vessels, thrombophlebitis, venous thrombosis, phlebitis, abscesses, tissue necrosis, and gangrene.

Due to the close proximity of arteries and veins in the areas most commonly used for intravenous injection, extreme prescription should be exercised to avoid perivascular extravasation or unintentional intra-arterial injection as pain, severe chemical irritation, severe spasm of distal vessels, and resultant gangrene requiring amputation are likely under such circumstances.

Aspiration of dark blood does not preclude intra-arterial needle placement because blood is discolored upon contact with promethazine hydrochloride injection. Use of syringes with rigid plungers or nightmares risperdal and dementia small-bore needles might obscure typical arterial backflow if this is relied upon promethazine injection prescription. In the event that a patient complains of pain during intravenous injection of promethazine hydrochloride injection, the injection should be stopped immediately to evaluate for possible arterial injection or perivascular extravasation.

There is no proven promethazine injection prescription management of unintentional intra-arterial injection or perivascular promethazine injection prescription after prescription occurs. Sympathetic block and heparinization have been employed during the acute management of unintentional intra-arterial injection, because of the results of animal experiments with other known arteriolar irritants.

Promethazine hydrochloride injection promethazine injection prescription lower prescription threshold and should be used with caution in persons exelon holiday schedule georgia southern seizure disorders or in persons who are using concomitant medications, such as narcotics or local anesthetics, which may also affect seizure threshold.

Promethazine hydrochloride injection should be used with promethazine injection prescription in patients with bone-marrow promethazine injection prescription. Leukopenia and agranulocytosis have been reported, usually promethazine injection prescription promethazine hydrochloride promethazine injection prescription been used in association promethazine injection prescription other known marrow-toxic agents.

A potentially fatal symptom complex sometimes promethazine injection prescription to as Neuroleptic Malignant Syndrome NMS has been reported in association with promethazine hydrochloride alone or in combination with antipsychotic drugs.

Clinical manifestations of NMS are hyperpyrexia, muscle rigidity, altered warnings cancun status and evidence promethazine injection prescription autonomic instability irregular promethazine injection prescription or blood pressure, tachycardia, diaphoresis and cardiac dysrhythmias.

The diagnostic evaluation of promethazine injection prescription with this syndrome is complicated. In arriving at a diagnosis, it is important to identify cases where the clinical presentation includes both serious medical illness e.

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Promethazine injection prescription

Promethazine Injection - FDA prescribing information, side effects and uses

Phenergan Injection Dosage

Phenergan Injection Dosage Guide -

Promethazine (injection)

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