Promethazine hydrochloride 90 mg

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Available forms Available by prescription promethazine hydrochloride Promethazine hydrochloride Children older than age 2: Prevention and treatment of nausea and vomiting. Routine preoperative or postoperative sedation or as an adjunct to analgesics. Maximum, mg daily.

Promethazine

Pharmacodynamics Antiemetic and promethazine hydrochloride actions: The central antimuscarinic actions of antihistamines probably are responsible for their antivertigo and antiemetic effects; promethazine also is believed to inhibit the medullary chemoreceptor trigger zone. Mechanism unknown; probably causes sedation by reducing stimuli to the brain-stem reticular system. Well absorbed from GI tract. Effects usually last 4 to 6 promethazine hydrochloride 90 mg but may last promethazine hydrochloride 12 promethazine hydrochloride.

Distributed widely throughout body; crosses the placental barrier. Metabolites excreted in urine and feces.

Promethazine hydrochloride | C17H21ClN2S - PubChem

Contraindications and precautions Contraindicated in patients hypersensitive to drug; in those with promethazine hydrochloride obstruction, prostatic hyperplasia, bladder neck obstruction, seizure disorders, coma, CNS depression, or stenosing peptic ulcerations; in newborns, premature neonates, and breast-feeding patients; promethazine hydrochloride in acutely ill or dehydrated children.

Use cautiously promethazine hydrochloride 90 mg patients with asthma or cardiac, pulmonary, or hepatic disease. Causes partial adrenergic blockade and further hypotension. Interferes with detoxification of antihistamines and phenothiazines; prolongs and intensifies sedative and anticholinergic effects. Other antihistamines or CNS depressants such as anxiolytics, barbiturates, sleeping aids, tranquilizers: Causes additive CNS depression.

Increases see more or severity of dystonic reactions. Increases risk of toxicity. Advise patient to take precautions. Overdose and treatment Toxicity may cause CNS depression sedation, reduced promethazine hydrochloride 90 mg alertness, apnea, and Promethazine hydrochloride collapse or CNS stimulation insomnia, hallucinations, tremors, promethazine hydrochloride 90 mg seizures.

promethazine hydrochloride

Atropine-like signs and symptoms, such as dry mouth, flushed skin, fixed and dilated pupils, and Promethazine hydrochloride symptoms, are common, especially click children.

Promethazine hydrochloride 90 mg hypotension with vasopressors, and control seizures with diazepam or phenytoin; correct acidosis and electrolyte imbalance.

Urinary acidification promotes excretion of drug. Drug may be administered I. Promethazine may cause either false-positive or false-negative pregnancy test results.

It also may interfere with blood promethazine hydrochloride in the ABO system. Many of these drugs appear in breast milk, exposing infants to risks of unusual excitability, especially premature infants and other neonates, who may experience seizures. Symptoms usually respond to a decrease in dosage.

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