Phenytoin 50 mg iv
Available forms Available by prescription only phenytoin Oral suspension: Once controlled, maintenance dose is mg /lisinopril-rxlist-xray.html. Also may administer phenytoin 50 mg phenytoin 50 mg iv loading dose of 1 g I.
PHENYTOIN | Drug | BNF content published by NICE
Can be diluted in normal saline solution. Prophylactic control of seizures during neurosurgery. Like other hydantoin derivatives, phenytoin stabilizes neuronal membranes and limits seizure /aleve-500-vs.html by either increasing phenytoin or decreasing influx of sodium ions across cell membranes phenytoin the motor cortex during generation phenytoin 50 mg iv nerve impulses.
Inhibits excessive collagenase activity in patients phenytoin epidermolysis bullosa. Absorbed slowly from small intestine; absorption is form-dependent and bioavailability may differ phenytoin 50 mg iv products.
Metabolized by liver to inactive metabolites. Excreted in urine; exhibits dose-dependent zero-order elimination kinetics.
Above a certain dosage level, small increases in dosage phenytoin increase serum levels. Contraindications and precautions Contraindicated in more info with hydantoin hypersensitivity, sinus bradycardia, SA block, second- or third-degree AV block, or Adams-Stokes syndrome.
Use cautiously in elderly or debilitated patients; phenytoin 50 mg iv those with hepatic dysfunction, hypotension, myocardial insufficiency, diabetes, or respiratory depression; and in those receiving just click for source derivatives.
Phenytoin interacts with many drugs. Diminished therapeutic effects and toxic reactions commonly are the result of recent changes in drug therapy. Allopurinol, amiodarone, benzodiazepines, chloramphenicol, chlorpheniramine, cimetidine, diazepam, disulfiram, phenytoin 50 mg iv, ibuprofen, imipramine, isoniazid, metronidazole, miconazole, omeprazole, phenacemide, phenylbutazone, salicylates, succinimides, trimethoprim, valproic acid: Increases therapeutic effects of phenytoin.
Phenytoin Sodium 50mg/ml Solution for Injection
Amiodarone, APAP, carbamazepine, corticosteroids, cyclosporine, phenytoin 50 mg iv, digitoxin, disopyramide, dopamine, doxycycline, estrogens, furosemide, haloperidol, hormonal contraceptives, levodopa, mebendazole, meperidine, methadone, metyrapone, phenothiazines, quinidine, sulfonylureas: Decreases effects of these phenytoin 50 mg iv via increased hepatic metabolism.
Adjust dosages as needed. Antacids, antineoplastics, barbiturates, calcium, continue reading gluconate, carbamazepine, charcoal, diazoxide, folic phenytoin 50 mg iv, phenytoin 50 mg iv, nitrofurantoin, pyridoxine, rifampin, sucralfate, theophylline: Decreases therapeutic effects of phenytoin.
Monitor serum lithium levels. May reduce orally administered phenytoin levels. Consider administering phenytoin 2 hours before starting enteral feeding, or wait 2 hours after stopping enteral feeding to administer phenytoin.
Overdose and treatment Early toxicity may cause drowsiness, nausea, vomiting, nystagmus, ataxia, dysarthria, phenytoin 50 mg iv, and slurred speech; then click, arrhythmias, respiratory depression, and coma. Death is caused by respiratory and phenytoin depression. Estimated lethal dose in adults is 2 to 5 g. Treat overdose with gastric lavage or emesis and follow with supportive treatment. Carefully monitor vital signs and er uses dementia depakote and phenytoin 50 mg iv balance.
Forced diuresis is of little or no value. Hemodialysis or peritoneal dialysis may be helpful. phenytoin 50 mg iv
Phenytoin Injection Dosage & Rx Info | Uses, Side Effects - MPR
During continuous tube feeding, tube should be flushed before and after dose. In-line filter is recommended. An alternative to breast-feeding is recommended during therapy.
Take extreme care to use correct strength. Changing brands may change effect.
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In a patient having continuous seizure activity, as compared to the more common rapidly recurring seizures, i. The loading dose should be followed by maintenance doses of mg orally or intravenously every 6 to 8 hours.
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Do not dilute solution in IV fluids. History of prior acute hepatotoxicity due to phenytoin. Heart block and sinus bradycardia.
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Initially by slow intravenous injection, or by intravenous infusion. The dose is the same for all phenytoin products when initiating therapy.
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