Phenergan injection site msds

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Medically reviewed on Sep 3, Phenergan Injection should not be used in pediatric patients less than 2 years of age because of the potential for fatal respiratory depression.

Postmarketing cases of respiratory depression, including fatalities, have been reported with use of promethazine in pediatric patients less than 2 years of age.

Phenergan Injection can cause severe chemical irritation phenergan injection site msds damage to tissues regardless of the route of administration.

Irritation phenergan injection site msds damage can phenergan injection site msds from perivascular extravasation, unintentional intra-arterial injection, and intraneuronal or perineuronal infiltration. Adverse reactions include burning, pain, thrombophlebitis, tissue necrosis, and msds. Due to the risks of intravenous injection, the preferred route of administration of Phenergan Injection is deep intramuscular injection.

Phenergan Injection - FDA prescribing information, side effects and uses

Subcutaneous injection is contraindicated. Each mL contains promethazine hydrochloride, either 25 /what-does-citalopram-do-quit.html or 50 mg, edetate disodium 0.

The product is light sensitive. It should be inspected before use and discarded if either color or particulate is observed.

Promethazine Hydrochloride Injection, USP (50 mg/mL x 25)

Promethazine hydrochloride is a phenothiazine derivative which possesses antihistaminic, sedative, antimotion-sickness, antiemetic, and anticholinergic effects. Promethazine is a competitive Phenergan injection site msds 1 receptor antagonist, but does not block the release of histamine.

Clinical effects are generally apparent within 5 minutes of an intravenous injection and within 20 phenergan injection site of an intramuscular injection.

Duration of action is four to six hours, although effects may persist up to 12 hours. Promethazine hydrochloride is metabolized in continue reading liver, with the sulfoxides of promethazine link N-desmethylpromethazine being the predominant metabolites appearing in the urine.

Following intravenous phenergan injection site msds in healthy volunteers, the plasma half-life for promethazine has been reported to range from 9 to 16 hours. The mean plasma half-life phenergan injection site msds promethazine phenergan injection site msds intramuscular administration in healthy volunteers has been reported to be 9.

Phenergan Injection

Phenergan Injection should not be given by the subcutaneous route because evidence of chemical irritation msds been noted, phenergan injection site msds necrotic lesions have resulted following subcutaneous injection.

The preferred parenteral route of administration is by phenergan injection site msds intramuscular injection. Phenergan Injection phenergan injection site msds contraindicated in patients who have demonstrated an idiosyncratic reaction or phenergan injection site msds to promethazine or other phenothiazines.

A wide range of weight-based doses of Phenergan injection site msds Injection have resulted in respiratory depression in these patients.

Caution should be exercised when administering Phenergan Injection to pediatric patients 2 years of age and older. Avoid concomitant administration of other drugs with respiratory depressant effects because of an association with respiratory depression, and sometimes death, in pediatric patients.

Promethazine Hydrochloride Injection, USP (50 mg/mL x 25) | X-Gen Pharmaceuticals, Inc

Because of the risk of site msds fatal respiratory depression, use of Phenergan Injection in patients with compromised respiratory function msds patients at risk for respiratory failure e. COPD, sleep apnea should be avoided.

Adverse event phenergan site msds site msds include burning, pain, erythema, swelling, sensory loss, palsies, paralysis, severe spasm of distal vessels, thrombophlebitis, venous thrombosis, phlebitis, abscesses, tissue necrosis, and phenergan injection.

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