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But the list also includes some surprises -- household name drugs that shouldn't be taken with ED pills -- including FlomaxProvigil and grapefruit juice.

Grapefruit and medication: A cautionary note - Harvard Health

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The use of multiple drug regimens is increasingly recognized as a tacit requirement for the management of hypertension, a necessity fueled in part by rising rates of metabolic syndrome and diabetes. By targeting complementary pathways, combinations of antihypertensive drugs can be applied to provide effective blood pressure control while minimizing side effects and reducing exposure to high doses of individual medications. In addition, combination therapies, including angiotensin converting enzyme ACE inhibitors and calcium channel blockers CCBs , have the added benefit of reducing cardiovascular mortality and morbidity over other dual therapies while providing equivalent blood pressure control.

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Sildenafil can add to the blood pressure-lowering effect of telmisartan. Contact your doctor if you experience signs and symptoms of low blood pressure such as dizziness, lightheadedness, fainting, flushing, headache, or a rapid pulse or heart rate.

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Grapefruit and grapefruit juice are healthful, providing enough vitamin C, potassium, dietary fiber, and other nutrients to earn the American Heart Association's "heart-check" mark. That's the good news. The bad news is that grapefruit juice can interact with dozens of medications, sometimes dangerously.