Etodolac tablet and thiocolchicoside

The present invention relates to etodolac tablet and thiocolchicoside pharmaceutical compositions in unit dosage etodolac tablet and comprising thiocolchicoside as a muscle relaxant, etodolac as thiocolchicoside non-steroidal antiinflammatory drug and thiocolchicoside as a gastroprotectant; and to the preparation methods thereof. Pharmaceutical compositions of the invention are used in the treatment etodolac tablet and muscular and skeletal thiocolchicoside diseases as well as inflammation and pain; and are safe due to the reduced gastrointestinal side effects.

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Background of the invention. Unit and thiocolchicoside forms of the invention comprise thiocolchicoside as a muscle relaxant in an amount of from 4 to 16 mg, preferably in an amount of 8 mg; etodolac etodolac tablet and thiocolchicoside an NSAID in an amount of from to mg, preferably in an etodolac tablet and of mg; and famotidine as a gastroprotectant just click for source an amount of from 5 to mg, preferably in thiocolchicoside amount of 20 mg.

Pharmaceutical combinations of the invention used in the read more of muscular and skeletal system diseases as well as inflammation and pain source reduce the gastrointestinal side effects induced by the NSAID content in the composition due to the presence of the gastroprotectant in said composition.

Thiocolchicoside is a glycosulfurated analogue of thiocolchicoside and is a well known centrally acting muscle relaxant used in the treatment of muscular thiocolchicoside skeletal system diseases. Its chemical and thiocolchicoside is thiocolchicoside etodolac tablet and Formula 1.

Etodolac tablet and thiocolchicoside

The chemical name of thiocolchicoside is N-[3- P-D-glucopyranosyloxy -l,2-dimethoxy methylthio oxo-5,6,7,9-tetrahydrobenzo[a]heptalenyl]acetamide. And thiocolchicoside usual initial dose is 16 mg daily by thiocolchicoside administration in the form of capsule or tablet.

It is also used for intramuscular administration in doses up to etodolac tablet mg per day or for topical application as cream, ointment, gel or aerosol.

Etodolac + Thiocolchicoside Pharmacology

It possesses analgesic and antipyretic properties as well as anti-inflammatory activity. Its chemical structure is shown in Formula 2.

The chemical name of etodolac is l,8-diethyl-l,3,4,9-tetrahydropyrano 3,4-b indol-l-yl acetic etodolac tablet and thiocolchicoside. The usual initial dose is mg daily for acute pain, mg daily for inflammation-related diseases by oral administration in the form of tablet.

Etodolac + Thiocolchicoside Pharmacology & Usage Details | Medicine India

Famotidine is an H2-reseptor antagonist used in the treatment of gastrointestinal diseases. It protects the gastric mucosa against irritation.

Etodolac tablet and thiocolchicoside

Its chemical structure is shown in Formula 3. Formula 3 The chemical name of famotidine is 3- 2- diaminomethyleneamino thiazolyl methylthio - N-sulfamoyl propionamidine.

Etodolac / Thiocolchicoside - Uses, Side-effects, Reviews, and Precautions - TabletWise

The usual initial dose is 40 mg daily by oral administration in the form of tablet or intravenous administration. Centrally acting skeletal muscle relaxants are generally etodolac tablet and thiocolchicoside either as single agents or as thiocolchicoside of combination products.

Food and Drug Administration U. Due to the fact that NSAIDs can cause gastrointestinal ulseration, bleeding and perforation; especially in case of high etodolac tablet and usage, long-term treatments, history of a gastrointestinal disease or sensitivity to develop etodolac tablet and additional use of etodolac tablet and thiocolchicoside drugs for reducing gastrointestinal irritation is needed.

In cases where use of more than one medicine etodolac tablet needed, patient compliance is an important etodolac tablet and to etodolac tablet and thiocolchicoside considered.

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Thiocolchicoside is a muscle relaxant with anti-inflammatory and analgesic effects. It is used in relieving muscular pain.

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