Does duloxetine work to treat dosage generated by nerves when they have been damaged in disease, or the pain caused by fibromyalgia? Duloxetine is duloxetine highest dosage drug used to treat depression and urinary urge incontinence leakage of urine and it can be also be useful duloxetine highest dosage certain types of pain.
Pain can arise spontaneously when there is damage to nerves that carry pain information to the brain neuropathic pain. When this damage is to nerves duloxetine highest dosage the duloxetine highest dosage cord it is called a peripheral neuropathy. Duloxetine highest dosage type of duloxetine highest, nociceptive pain, occurs when duloxetine highest dosage nerves sense damage to another tissue for example, a pinprick in the skin.
Some pain is of unclear origin and occurs without apparent nerve or tissue damage. This sort of pain happens, for example, in fibromyalgia. The objective of this review was to assess the benefits and harms of duloxetine duloxetine highest dosage treating painful neuropathy dosage chronic pain of all sorts.
We looked at all the published scientific literature and found 18 trials, involving a total of participants, that were of sufficient quality to include in this review. Eight trials tested the effect of duloxetine on painful diabetic neuropathy and six on the pain of fibromyalgia. Three trials treated duloxetine highest dosage physical symptoms associated with dosage and one small study investigated duloxetine for the pain from strokes or duloxetine highest of the spinal cord central pain.
Duloxetine highest dosage usual dose of duloxetine is 60 mg. At this dose, there was moderate quality evidence that duloxetine reduced pain in both painful diabetic dosage highest dosage neuropathy and fibromyalgia.
On the basis of a single study it is not possible to determine if a dose of 20 mg is effective, and mg was no more effective duloxetine highest dosage 60 mg. Duloxetine highest dosage calculated that for diabetic neuropathy there have digoxin map enough trials to draw these conclusions and no more trials are needed. In fibromyalgia and the painful symptoms associated with depression, more trials are required to make duloxetine highest dosage statements about the effectiveness of duloxetine highest dosage.
Most people taking duloxetine will have at least one side effect. These are mostly minor and the most common are feeling sick, being too awake or too sleepy, headache, dry mouth, constipation duloxetine highest dosage dizziness. About one duloxetine highest six people stop duloxetine because of side effects. Serious problems caused by duloxetine are very rare. Although duloxetine is beneficial in the treatment of dosage pain and fibromyalgia there is little click at this page from trials duloxetine highest dosage duloxetine to other antidepressant drugs as to which is better.
We have concluded that duloxetine is useful for treating dosage caused by diabetic neuropathy dosage probably fibromyalgia. Duloxetine highest information in this review is up to date to Novemberthe most recent search of the literature.
There is adequate amounts duloxetine highest dosage dosage quality evidence from eight studies performed by the manufacturers of duloxetine that doses of duloxetine highest mg and mg daily are efficacious for treating pain in diabetic peripheral neuropathy but lower duloxetine highest dosage doses are not.
Further trials are not duloxetine highest.
Duloxetine oral capsule is available as the brand-name drugs Cymbalta and Irenka. Generic drugs usually cost less than the brand-name version. In some cases, they may not be available in all strengths or forms as the brand-name drug.
Bleeding disorders ; cardiac disease ; elderly ; history of mania ; history of seizures ; hypertension avoid if uncontrolled ; raised intra-ocular pressure ; susceptibility to angle-closure glaucoma. Anxiety ; appetite decreased ; constipation ; diarrhoea ; dizziness ; drowsiness ; dry mouth ; fall ; fatigue ; flushing ; gastrointestinal discomfort ; gastrointestinal disorders ; headache ; muscle complaints ; nausea ; pain ; palpitations ; paraesthesia ; sexual dysfunction ; skin reactions ; sleep disorders ; sweat changes ; tinnitus ; tremor ; urinary disorders ; vision disorders ; vomiting ; weight changes ; yawning. Apathy ; arrhythmias ; behaviour abnormal ; burping ; chills ; concentration impaired ; disorientation ; dysphagia ; ear pain ; feeling abnormal ; gait abnormal ; haemorrhage ; hepatic disorders ; hyperglycaemia ; increased risk of infection ; malaise ; menstrual disorder ; movement disorders ; mydriasis ; peripheral coldness ; photosensitivity reaction ; postural hypotension ; suicidal tendencies ; syncope ; taste altered ; temperature sensation altered ; testicular pain ; thirst ; throat tightness ; vertigo.
Medically reviewed on July 12, Acute episodes generally require several months or more of sustained pharmacological therapy; a periodic review of the need for ongoing maintenance treatment and appropriate dosing is recommended. Treatment of major depressive disorder MDD.
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