Dose of methotrexate in psoriasis consensus conference
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B Level of Evidence: Oral methotrexate is an effective treatment for psoriasis being initially used more than 50 years ago. Methotrexate competitively inhibits the enzyme dihydrofolate reductase, thus decreasing the synthesis of folate cofactors needed to produce nucleic acids.
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Methotrexate remains a valuable option for the treatment of psoriasis. This report will summarize studies regarding the use of methotrexate since the last guidelines were published in
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