Dilantin package insert 7 year old

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Medically reviewed on Nov 1, Link Oral Suspension is indicated for the treatment of tonic-clonic grand mal and psychomotor temporal lobe seizures. A calibrated measuring device is recommended old measure and deliver the prescribed dose accurately.

A household teaspoon or tablespoon is not an adequate dilantin package insert 7 year old device. Adjust the dosage to suit individual requirements, up to a maximum of 25 mL daily [see Dosage old Administration old.

Dosage should be individualized to provide maximum benefit. In some cases, serum blood level determinations may be necessary for optimal dosage adjustments.

Trough levels provide information about clinically dilantin package insert serum level range and confirm patient compliance, and are obtained just prior to the patient's next scheduled dose.

Peak levels indicate an individual's threshold for emergence of dose-related side effects and are obtained at the dilantin package insert 7 year old of expected peak concentration.

In patients with renal or hepatic disease, or in those with hypoalbuminemia, the monitoring of unbound phenytoin old may be more relevant [see Dosage and Administration old. Old recommended dosages, old period of seven to ten days may be required to achieve phenytoin steady-state blood levels, and changes in dosage increase or decrease should not be carried out at intervals shorter than seven old ten days.

Phenytoin extended capsules dilantin package parental Phenytoin Oral Suspension are formulated with the sodium salt of phenytoin. Because the fraction of unbound phenytoin is dilantin package insert 7 year old in patients with renal or hepatic disease, or in insert year with hypoalbuminemia, the monitoring of phenytoin serum levels should be based on the unbound fraction in those patients [see Warnings and Precautions 5.

Phenytoin clearance is decreased slightly in link patients and lower or less frequent dosing may be required [see Clinical Pharmacology Decreased serum concentrations of phenytoin may occur during pregnancy because of altered phenytoin pharmacokinetics.

Phenytoin Oral Suspension

Periodic measurement of serum phenytoin insert year should be performed during pregnancy, and the Phenytoin Oral Suspension dosage should be adjusted as necessary. Postpartum restoration of the original dosage will probably year old indicated [see Use in Specific Populations 8.

Because of dilantin package changes in protein binding during pregnancy, the monitoring of phenytoin serum levels dilantin package insert 7 year old be based on the unbound fraction. Abrupt withdrawal of phenytoin dilantin package insert 7 year old epileptic patients may precipitate status epilepticus. When in the judgment of the clinician the need for dosage reduction, discontinuation, or substitution of alternative anticonvulsant medication arises, this should be done gradually.

However, in the event of an allergic or hypersensitivity reaction, more rapid substitution of alternative therapy may be necessary. In this case, alternative dilantin package insert 7 year old should be an anticonvulsant not belonging to the hydantoin chemical class.

Antiepileptic drugs AEDsincluding Phenytoin Oral Suspension, increase the risk of suicidal thoughts or behavior in patients taking these drugs for any indication. Pooled analyses of placebo-controlled clinical trials dilantin package insert 7 year old and adjunctive therapy of 11 different AEDs showed that patients randomized to one of the AEDs had approximately twice the risk adjusted Relative Risk 1.

Phenytoin Oral Suspension - FDA prescribing information, side effects and uses

In these trials, which had a median treatment duration of 12 weeks, the estimated incidence rate of suicidal behavior or ideation among 27, AED-treated patients was 0. There were four suicides in drug-treated patients in the trials and none in placebo-treated patients, but the dilantin package insert 7 year old is too small to allow any conclusion about drug effect on suicide.

The increased risk of suicidal thoughts or behavior with AEDs was observed as early as one week after starting drug treatment with AEDs and persisted for dilantin package insert 7 year old duration of treatment assessed.

Because most trials included in the analysis did not extend beyond 24 weeks, the risk of suicidal thoughts or behavior /allergic-reaction-to-voltaren-gel-webmd.html 24 weeks could not be assessed.

The risk of suicidal thoughts or behavior was generally consistent among drugs in the data analyzed. The finding of increased risk with AEDs of varying mechanisms of action and across a range of indications suggests that the risk applies to all AEDs used for any indication.

The risk did not vary substantially by dilantin package insert 7 year old 5 dilantin package insert 7 year old years in the clinical trials analyzed. The relative risk for suicidal thoughts or behavior was higher in clinical trials for epilepsy than in clinical trials for psychiatric or other conditions, but the absolute risk differences were similar for the doxycycline hyclate used what is taken for and psychiatric indications.

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