Digoxinsold under the brand name Lanoxin among others, is a medication used to treat various heart conditions. Common side effects include breast enlargement with digoxin sandoz wiki side effects generally due to an excessive dose.
Digoxin was first isolated in from the foxglove plant, Digitalis lanata. There is tentative evidence that digoxin may increase the risk of death, [12] though another meta-analysis in reported no change in mortality.
digoxin sandoz wiki
Digoxin is no longer the first digoxin sandoz wiki for heart failure ; digoxin sandoz wiki has fallen out of favor in people with heart failure because it may increase the risk of digoxin sandoz. Digoxin is a 3rd line therapy. Digoxin wiki also used intrafetally or amniotically during abortions in the late second trimester and third trimester of digoxin sandoz wiki.
It typically causes fetal demise digoxin sandoz wiki by cessation of cardiac activity within hours of administration. The occurrence of adverse drug reactions is common, owing to its narrow therapeutic index the margin between effectiveness and toxicity. Digoxin sandoz wiki enlargement of breast tissue is mentioned in many textbooks as a side effect, thought to be due to the estrogen -like steroid moiety of the digoxin molecule, [16] but when systematically sought, digoxin sandoz wiki digoxin sandoz wiki for this is equivocal.
In overdose, the usual supportive measures are needed.
Digoxin is usually given orally, but can also be given by IV injection in urgent situations the IV injection should be slow, digoxin sandoz wiki heart rhythm should be monitored. While IV therapy may be better tolerated less nauseadigoxin digoxin sandoz wiki digoxin sandoz wiki very long distribution half-life into the digoxin sandoz tissue, which will delay its onset of action by wiki number of hours.
Digoxin wiki is mainly by renal excretion and involves P-glycoproteinwhich leads to significant clinical interactions with P-glycoprotein inhibitor drugs. Examples commonly used in patients with heart problems include spironolactoneverapamil and amiodarone.
In patients with decreased kidney function the digoxin sandoz wiki is considerably longer, along with decrease in Vd volume of distributioncalling for a /bupropion-wellbutrin-sr-positive.html digoxin sandoz wiki dose or a switch to a different glycosidesuch as click not available in the United Stateswhich has a much longer elimination half-life of around seven days and is eliminated by the liver.
Digoxin sandoz wiki plasma levels vary depending on the medical indication.
Wiki congestive heart failure digoxin digoxin sandoz wiki, levels between 0. For heart rate control atrial fibrillation digoxin sandoz wiki, plasma levels are less defined and are generally titrated to a goal heart rate. Typically, digoxin levels are considered digoxin sandoz wiki for heart rate control between 0.
Sotalol is a medication used to treat abnormal heart rhythms. Food and Drug Administration FDA advises that sotalol only be used for serious abnormal heart rhythms, because its prolongation of the QT interval carries a small risk of life-threatening polymorphic ventricular tachycardia known as torsade de pointes.
Digoxin is a widely used medication that is effective for many cardiac conditions in adults and children. Some side effects are expected, some are common but serious, some are uncommon and not serious and others are rare but serious.
Digitek, Digox, Lanoxin, Lanoxicaps, Cardoxin. Medically reviewed by P.
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