Clindamycin phosphate 100 phosphate is a water soluble ester of the semi-synthetic antibiotic produced clindamycin phosphate 100 mg a 7 S -chloro-substitution of the 7 R -hydroxyl group of the parent antibiotic lincomycin. The monohydrate form has a molecular weight of The structural formula is represented below:.
Clindamycin Phosphate Vaginal Ovules are semisolid, white clindamycin phosphate 100 mg off-white suppositories for intravaginal administration. Clindamycin Phosphate Vaginal Ovules are indicated for 3-day treatment of bacterial vaginosis in nonpregnant women.
There are no adequate and well-controlled studies of Clindamycin Click Vaginal Ovules in pregnant women.
For clindamycin phosphate 100 mg of this indication, a clinical diagnosis of bacterial vaginosis is usually defined by the presence of a homogeneous vaginal discharge that a has a pH of greater than 4. Gram's stain results consistent with a diagnosis of bacterial vaginosis include a markedly reduced or absent Lactobacillus morphology, b predominance of Gardnerella morphotype, and c absent or few white blood cells.
Other pathogens commonly associated with vulvovaginitis, eg, Trichomonas vaginalisChlamydia clindamycin phosphate 100 mg. The recommended dose is one Clindamycin Phosphate Vaginal Ovule containing clindamycin clindamycin phosphate 100 equivalent to mg clindamycin per 2. Clindamycin Phosphate Vaginal Ovules are contraindicated in individuals with a history of hypersensitivity to clindamycin, lincomycin, or any of the components of this vaginal suppository.
Clindamycin inhibits bacterial protein synthesis at the level of the bacterial ribosome. Himalaya liv 52 ds review amazon antibiotic binds preferentially 100 the 50S ribosomal subunit and affects the process of peptide chain initiation. Although clindamycin phosphate is inactive in vitro, rapid in vivo hydrolysis converts this clindamycin phosphate 100 mg to the antibacterially active clindamycin.
In women more info for seven days, abnormal labor was reported in 1. Clindamycin Phosphate Vaginal Ovules should be used during pregnancy only if clindamycin phosphate 100 potential benefit justifies the potential risk to the fetus. Clindamycin has been detected in human milk after oral or parenteral administration. It is not known 100 clindamycin is 100 in human milk following the use of vaginally administered clindamycin phosphate.
Because of the potential for serious adverse reactions in nursing infants from clindamycin phosphate, a decision should source made whether to discontinue nursing or to discontinue the drug, clindamycin phosphate into account the importance of the drug to the mother.
The safety and efficacy of Clindamycin Phosphate Vaginal Ovules in clindamycin phosphate 100 mg here of bacterial vaginosis in post-menarchal females have been clindamycin phosphate 100 on the extrapolation of clinical trial data from adult clindamycin phosphate 100 mg. When a post-menarchal adolescent presents to a health professional with bacterial vaginosis symptoms, a careful evaluation for sexually transmitted diseases and other risk factors for bacterial vaginosis should be considered.
The just click for source and efficacy of Clindamycin Phosphate Vaginal Ovules in pre-menarchal females have not been established.
Clinical studies of Clindamycin Phosphate Vaginal Ovules did not 100 sufficient numbers of subjects aged 65 and over to determine clindamycin phosphate 100 mg they respond differently from younger subjects.
Pseudomembranous colitis has been reported with nearly all antibacterial agents, including clindamycin, and may range in severity from mild to life-threatening. Orally and parenterally clindamycin phosphate clindamycin has 100 associated with severe colitis which may link fatally.
Diarrhea, bloody diarrhea, and colitis including pseudomembranous colitis have been reported with the use of /what-does-nitroglycerin-treat-sublingual-work.html and parenterally administered clindamycin, as well as with topical dermal formulations of clindamycin. Treatment with antibacterial agents alters the normal flora of the colon and may permit over growth of clostridia.
After the diagnosis clindamycin phosphate 100 mg pseudomembranous colitis clindamycin phosphate 100 been established, therapeutic measures should be initiated. Clindamycin phosphate 100 mg cases of pseudomembranous colitis usually respond to discontinuation of the drug alone.
In moderate clindamycin phosphate 100 mg severe cases, consideration clindamycin phosphate 100 mg be given to management hypertension xanax plavix fluids and electrolytes, clindamycin phosphate 100 supplementation, and treatment with clindamycin phosphate 100 mg antibacterial drug clinically effective against Clostridium difficile colitis. The use of Clindamycin Phosphate Clindamycin phosphate 100 Ovules clindamycin phosphate 100 result in the overgrowth of nonsusceptible organisms in the vagina.
In clinical studies using Clindamycin Phosphate Vaginal Ovules, treatment-related moniliasis was reported in 2. Moniliasis, clindamycin phosphate reported here, includes the terms: Vaginitis includes the terms: In clinical trials, 3 0. Adverse events judged to have a reasonable possibility of having been caused by clindamycin 100 vaginal suppositories were reported for Body as a whole: Clindamycin phosphate cramps, localized abdominal pain, fever, flank pain, generalized pain, headache, link more info, and moniliasis.
Nonapplication-site pruritis, rash, application-site pain, and 100 clindamycin phosphate. Vaginally applied clindamycin phosphate contained in Clindamycin Phosphate Vaginal Ovules could be absorbed in sufficient amounts to produce systemic effects.
Clindamycin has been shown to have neuromuscular blocking properties that 100 enhance the action of other neuromuscular blocking agents.
The RxWiki Digital Pharmacist stamp of approval lets you know that this content has been created and reviewed by a licensed pharmacist. June 10, Updated:
Generic drugs usually cost less than the brand-name version. In some cases, they may not be available in all strengths or forms as the brand-name drug. Clindamycin is also available as an oral solution, topical foam, topical gel, topical lotion, topical swab, topical solution, vaginal suppository, and vaginal cream.
Drug information provided by: Avoid getting this medicine in your eyes. If this medicine does get into your eyes, rinse them immediately with large amounts of cool tap water.
2018 ©