Chloramphenicol 1 eye ointment grey baby syndrome
Gray baby syndrome also termed Syndrome or Grey syndrome is a rare but serious side effect that occurs in newborn infants especially premature babies following the accumulation of antibiotic chloramphenicol.
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Toxic levels of chloramphenicol after 2—9 days result in:. Two pathophysiologic mechanisms are thought to play a role in the development of article source baby grey baby after exposure to eye ointment anti-microbial link chloramphenicol.
This condition is due to a lack of glucuronidation reactions occurring in the baby, chloramphenicol leading to an accumulation of toxic chloramphenicol metabolites: Due to these two reasons the chloramphenicol level in blood is increased, at higher concentration chloramphenicol blocks electron transport in the liver, myocardium, and skeletal muscles, resulting the above symptoms.
The condition can be prevented by syndrome chloramphenicol at the recommended doses and monitoring blood levels, [3] syndrome [5] or alternatively, third generation cephalosporins can be effectively substituted chloramphenicol 1 eye ointment grey baby syndrome the drug, without syndrome associated toxicity. Chloramphenicol therapy should be stopped immediately.
Exchange transfusion may be required to remove the drug. Syndrome, phenobarbital UGT induction is used. From Wikipedia, the free encyclopedia.
CHLORAMPHENICOL | Drug | BNF content published by NICE
Not to be confused with Bronze baby syndrome. This section is empty. You can help by adding to it. British Medical Journal Clinical research ed.
CHLORAMPHENICOL | Drug | BNFc content published by NICE
Indian journal of pediatrics. Placenta praevia Placental insufficiency Twin-to-twin transfusion syndrome.
Just click for source cord prolapse Nuchal cord Single umbilical artery. Intrauterine hypoxia Infant respiratory distress syndrome Transient tachypnea of the newborn Meconium aspiration syndrome pleural disease Pneumothorax Pneumomediastinum Wilson—Mikity syndrome Bronchopulmonary dysplasia. Pneumopericardium Persistent fetal circulation.
Gray baby syndrome - Wikipedia
Grey baby Necrotizing enterocolitis Meconium peritonitis. Erythema toxicum Sclerema neonatorum. Perinatal asphyxia Periventricular leukomalacia. Gray baby syndrome muscle tone Eye ointment hypertonia Congenital hypotonia. Vertically transmitted infection Neonatal infection Congenital rubella syndrome Neonatal herpes check this out Mycoplasma hominis infection Ureaplasma urealyticum infection Chloramphenicol Neonatal sepsis Chloramphenicol 1 eye ointment grey baby syndrome B streptococcal infection Neonatal conjunctivitis.
Miscarriage Perinatal mortality Eye ointment grey Infant mortality Neonatal withdrawal. Retrieved from " https: Poisoning by drugs, medicaments and baby syndrome substances Syndromes. Infobox medical condition new Articles to be expanded from March All articles chloramphenicol be expanded Link with empty sections from March All articles with empty sections Articles using small message boxes.
Gray baby syndrome
syndrome Syndrome Read Edit View history. This page was last edited on 2 Decemberat By using this site, you eye ointment to the Terms of Use and Privacy Policy. D ICD - Respiratory Intrauterine hypoxia Infant respiratory distress syndrome Transient tachypnea of the newborn Meconium grey baby syndrome pleural disease Pneumothorax Pneumomediastinum Chloramphenicol syndrome Bronchopulmonary dysplasia.
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Every expecting mother wants her baby to be healthy. This is why they get prenatal care from their doctors and take other precautions to ensure a healthy pregnancy.
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For less severe infection 3—4 times daily is generally sufficient. Apply daily, to be applied at night if eye drops used during the day , alternatively apply 3—4 times a day, if ointment used alone. By mouth, or by intravenous injection, or by intravenous infusion.
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For less severe infection 3—4 times daily is generally sufficient. Apply daily, to be applied at night if eye drops used during the day , alternatively apply 3—4 times a day, if ointment used alone.
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