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Opipramol , sold under the brand name Insidon among others, is an anxiolytic and antidepressant which is used throughout Europe. Opipramol was developed by Schindler and Blattner in
Venlafaxine , sold under the brand name Effexor among others, is an antidepressant of the serotonin-norepinephrine reuptake inhibitor SNRI class. First introduced by Wyeth in , now marketed by Pfizer , it is licensed for the treatment of major depressive disorder MDD , generalized anxiety disorder GAD , panic disorder , and social phobia. A comparative meta-analysis of 21 major antidepressants found that venlafaxine, agomelatine , amitriptyline , escitalopram , mirtazapine , paroxetine , and vortioxetine were more effective than other antidepressants although the quality of many comparisons was assessed as low or very low.
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